Abstract: Grasslands serve as both the production base for animal husbandry and an important ecological shelter as well, while the widespread imbalance between grass resources and livestock has become one of the major factors damaging the grassland ecosystem. Achieving precise regulation of animal husbandry activities on the basis of effective animal husbandry space planning is crucial for grassland ecological protection and grass-livestock balance. Although previous scholars have carried out extensive research on the relationship between different grazing systems and plateau grassland ecosystems, there are still limited research related to the optimization of spatial layout and refined management of animal husbandry production in the field of territorial space planning. Using Zoige County as a case study, this study tries to establish a refined zoning method for livestock production activities through grass-livestock balance measurement and ecological condition assessment, which explores the optimization and management strategy of livestock production space layout in the highly ecologically sensitive Qinghai-Tibet Pastoral Area at the county scale. This study aims to address the research gap in spatial fine planning layout and control of livestock production activities in the field of spatial planning, while providing new planning ideas for realizing the balance of grass and livestock in the pastoral areas of the Qinghai-Tibet Plateau.